What is sodium benzoate injection used for?

Caffeine and sodium benzoate injection is used with other supportive therapies to treat respiratory depression (very slow breathing) caused by taking too much narcotic pain medicines or alcohol.

What kind of drug is benzoate?

Benzyl benzoate is an organic compound which is used as a medication and insect repellent. As a medication it is used to treat scabies and lice. For scabies either permethrin or malathion is typically preferred. It is applied to the skin as a lotion.

How do you take sodium benzoate?

Sodium benzoate is typically dosed for adults at 2–5 g orally twice daily. It is supplied as a bulk powder that can be measured and mixed into a favored beverage or food supplement.

How do you dilute Ammonul?

Components of Infusion Solution AMMONUL must be diluted with sterile 10% Dextrose Injection at ≥25 mL/kg before administration.

Is benzoate a narcotic?

Benzonatate, a non-narcotic oral antitussive agent, is 2, 5, 8, 11, 14, 17, 20, 23, 26-nonaoxaoctacosan-28-yl p-(butylamino) benzoate; with a molecular weight of 603.7. Each soft gelatin capsule, for oral administration, contains 100 mg or 200 mg of benzonatate USP.

How does caffeine and sodium benzoate work?

The drug also stimulates gastric acid secretion from parietal cells. Caffeine increases renal blood flow and glomerular filtration rate and decreases proximal tubular reabsorption of sodium and water, resulting in mild diuresis.

What medicines contain sodium benzoate?

Top Medications with this Excipient

  • Alprazolam 1 mg.
  • Alprazolam 2 mg.
  • Alprazolam 2 mg.
  • Alprazolam 0.5 mg.
  • Alprazolam 2 mg.
  • Alprazolam 0.25 mg.
  • Alprazolam 0.5 mg.
  • Alprazolam 2 mg.

What are the benefits of sodium benzoate?

Sodium benzoate inhibits the growth of potentially harmful bacteria, mold, and other microbes in food, thus deterring spoilage. It’s particularly effective in acidic foods ( 6 ). Therefore, it’s commonly used in foods, such as soda, bottled lemon juice, pickles, jelly, salad dressing, soy sauce, and other condiments.

How do you prepare Ammonul?


  1. AMMONUL must be diluted with sterile 10% Dextrose Injection (D10W) before administration.
  2. AMMONUL is administered intravenously as a loading dose infusion administered over 90 to 120 minutes, followed by an equivalent maintenance dose infusion administered over 24 hours. (

What is sodium phenylacetate and benzoate injection used for?

Descriptions. Sodium phenylacetate and benzoate injection combination is used to treat hyperammonemia, which is a condition where there is too much ammonia in the blood. Ammonia is formed from the breakdown of protein in the body. If the ammonia cannot be removed by the body, high amounts in the blood may cause serious unwanted effects.

What is sodium phenylacetate made from?

Sodium Phenylacetate is the sodium salt form of phenylacetate with ammonia detoxifying activity. Upon administration, sodium phenylacetate binds to glutamine thereby forming phenylacetylglutamine and is thus excreted by the kidneys.

How is sodium phenylacetate metabolized in the liver?

Sodium phenylacetate and sodium benzoate are metabolized in the liver; limited information available in impaired hepatic function. 1 Sodium phenylacetate and sodium benzoate are metabolized and excreted by the kidneys; renal clearance of drug metabolites and ammonia is required. 1

How much sodium phenylacetate do you give a child?

Pediatric patients weighing >20 kg: Loading dose of 5.5 g/m 2 sodium phenylacetate and 5.5 g/m 2 sodium benzoate infused over 90–120 minutes. 1 3 Maintenance dose of 5.5 g/m 2 sodium phenylacetate and 5.5 g/m 2 of sodium benzoate infused over 24 hours. 1 3