What causes Jaccoud arthropathy?

Currently, the more common cause of Jaccoud arthropathy in young patients is systemic lupus erythematosus. It has also been reported in various diseases including other connective tissue diseases or crystal-induced arthropathies. Jaccoud arthropathy may be misleading and suggestive of rheumatoid arthritis.

What is JAccoud arthropathy?

Jaccoud arthropathy (JA) is a non-erosive, deforming arthropathy of the metacarpophalangeal (MCP) and proximal interphalangeal joints, wrists and knees, first described as a rare complication of recurrent rheumatic fever1 and then extensively observed in systemic lupus erythaematosus (SLE) patients.

What is Rhupus?

The term rhupus refers to the coexistence of erosive symmetrical polyarthritis, typical manifestation of rheumatoid arthritis (RA), and clinical signs of SLE in the presence of anti double-stranded DNA (anti-dsDNA) and/or anti-Smith antibodies (anti-Sm) [2].

What is chronic Postrheumatic arthropathy?

Jaccoud’s arthropathy is typically observed in rheumatic fever, but it has also been described in systemic lupus erythematosus and other connective tissue disorders (1, 2). The deformities are reducible and are primarily caused by soft tissue abnormalities rather than destruction of the joints.

How is Jaccoud arthropathy treated?

Treatment. The focus of treatment is toward alleviating pain and maintaining functionality of the affected joints through use of nonsteroidal anti-inflammatory drugs, corticosteroids, antimalarial drugs and physiotherapy. Surgery is also a possibility, with osteotomy or stabilization with Kirschner intramedullary wire.

What is the predominant physical finding for SLE?

Musculoskeletal. Arthritis of the proximal interphalangeal (PIP) and metacarpophalangeal (MCP) joints of the hands, as well as the wrists, is the most common musculoskeletal finding in SLE. Tenderness, edema, and effusions accompany a polyarthritis that is symmetric, nonerosive, and usually nondeforming.

What is overlap syndrome?

Overlap syndromes are inflammatory rheumatic conditions in which patients have clinical manifestations suggestive of multiple distinct immune diseases. The diseases most commonly involved in overlap syndromes include rheumatoid arthritis, lupus, scleroderma, and myositis.

What is sarcoid arthropathy?

Sarcoid Arthropathy is a common manifestation of a rare disease. Sarcoid Arthropathy, being a mimic of multiple inflammatory arthropathies such as rheumatoid arthritis and seronegative Spondyloarthropathies, is often misdiagnosed as one of them.

What are the symptoms of acute leukemia?

You experience unexplained bleeding, high fever, or a seizure. You may need emergency treatment for acute leukemia. You are in remission from leukemia and notice signs of recurrence, such as infection or easy bleeding.

What to know about leukaemia?

Leukemia 1 Overview. Leukemia is cancer of the body’s blood-forming tissues,… 2 Symptoms. Leukemia symptoms vary, depending on the type of leukemia. 3 Causes. Scientists don’t understand the exact causes of leukemia. 4 Risk factors. Previous cancer treatment. People who’ve had certain types…

Should I talk to my doctor about my leukemia symptoms?

Make an appointment with your doctor if you have any persistent signs or symptoms that worry you. Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. Rarely, leukemia may be discovered during blood tests for some other condition.

What happens to normal blood cells in leukemia patients?

This happens when the leukemia cells in the bone marrow crowd out the normal blood-making cells. Consequently, patients with ALL do not have sufficient numbers of mature red blood cells, white blood cells and platelets.