Is methylene blue hazardous?

Causes eye irritation and possible injury. Skin: Causes skin irritation. Absorption into the body may cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood). Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea.

Does methylene blue require PPE?

PERSONAL PROTECTIVE EQUIPMENT: Wear eye protection, lab coat and gloves for routine operations. Avoid inhalation, contact with eyes and skin. Ensure access to safety shower and eye bath. The product contains no substances with occupational exposure limit values.

How do you handle methylene blue?

Handling: Use with adequate ventilation and do not breathe dust or vapor. Avoid contact with skin, eyes, or clothing. Wash hands thoroughly after handling. Storage: Store in General Storage Area [Green Storage] with other items with no specific storage hazards.

What is methylene blue made of?

Methylene blue is synthesized commercially by oxidation of N,N-dimethyl-phenylenediamine with sodium dichromate (Na2Cr2O7) in the presence of sodium thiosulfate (Na2S2O3), followed by further oxidation in the presence of N,N-dimethylaniline (NTP, 2008).

Is methylene blue safe to inhale?

May cause a short period of rapid or difficult breathing. Ingestion: A burning sensation of the mouth may be noted following ingestion of methylene blue. May cause nausea, vomiting, diarrhea, and gastritis.

What are the side effects of methylene blue?


  • Agitation.
  • bluish-colored lips, fingernails, or palms.
  • confusion.
  • dark urine.
  • difficulty breathing.
  • dizziness or lightheadedness.
  • fever.
  • headache.

Can methylene blue go down the drain?

Dispose of solution by neutralizing with dilute hydrochloric acid, and flush the neutral- ized solution down the drain with excess water according to Flinn Suggested Disposal Method #10. An extension of this activity uses a 0.1% resazurin solution in place of the methylene blue solution.

Who should not take methylene blue?

You should not be treated with methylene blue if you are allergic to it, or if you have: a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency.

What is methylene blue good for?

Methylene blue injection is used to treat a condition called methemoglobinemia. This condition occurs when the blood cannot deliver oxygen where it is needed in the body. This medicine is to be given only by or under the supervision of a doctor.

Can methylene blue be given orally?

Methylene Blue Injection may be administered orally or by intravenous injection. In the treatment of acute methaemoglobinaemia, the intravenous route of administration is usually preferred because it provides a more rapid onset of effect.

Is methylene blue FDA approved?

Because methylene blue is not an FDA-approved drug at this time, and limited data exist regarding its use in various settings, it is not known whether there is a risk of serotonin syndrome in patients taking serotonergic psychiatric medications who are given methylene blue by other routes (e.g., orally or by local …

Is methylene blue safe for humans?

Methylene blue is a safe drug when used in therapeutic doses (<2mg/kg). But it can cause toxicity in high doses.