How rare is a solitary fibrous tumor?

Introduction. Solitary fibrous tumor (SFT) is a rare soft tissue neoplasm, with an incidence of about 0,2/100.000/years. It was called “haemangiopericytoma” by Stout and Murray in 1942.

What is a solitary fibrous sarcoma?

Solitary fibrous tumor (SFT) is a rare soft tissue sarcoma subtype which mainly affects adults in the fifth and sixth decades of life. Originally part of a spectrum of tumors called hemangiopericytomas, classification has been refined such that SFTs now represent a distinct subtype.

What causes fibrous tumors?

Benign Fibrous Tumors of the Pleura. The pleura is the smooth, pale yellow transparent membrane that lines the thorax and protects the lungs. The most common tumors that occur in the pleura are cancerous forms of mesothelioma caused by exposure to asbestos.

What is solitary fibrous fibrous tumor?

Solitary fibrous tumor represents a spectrum of mesenchymal tumors, encompassing tumors previously termed hemangiopericytoma, which are classified as having intermediate biological potential (rarely metastasizing) in the 2002 World Health Organization classification scheme. Few series have reported …

What are soft tissue tumors (SFTS)?

Conclusions SFTs are a rare slow-growing mesenchymal tumor that has been differentiated from other soft tissue tumors over the past decades through advances in histology and molecular genetics.

What are the risk factors for malignant behavior in resected fibrous tumors?

Gholami S, Cassidy MR, Kirane A, et al. Size and location are the most important risk factors for malignant behavior in resected solitary fibrous tumors. Ann Surg Oncol2017;24:3865-71. 10.1245/s10434-017-6092-z [PubMed] [CrossRef] [Google Scholar]

What is the pathophysiology of spindle fibrosis (SFT)?

The differential is typically vast and SFT is usually not high on this differential given the relative rarity. Classically, SFTs are composed of spindle to ovoid cells arranged in patternless distribution with areas of tumor cells and other hypocellular regions with higher percentage of stromal collagen (6,15,27).